The impact of methylation on dopamine and other neurotransmitters has a profound impact on how fluid and stable our mental states are, which in turn influences the risk of many psychiatric disorders such as anxiety disorders, depression, bipolar disorder, ADHD, and substance abuse. Although B12 and folate are the best-known nutrients to support methylation, many others are just as critical: thiamin, niacin, riboflavin, vitamin B6, magnesium, choline, betaine, methionine, creatine, and glycine to name some of the key players. This talk outlines nutritional strategies to balance methylation with foods and supplements and looks at how genetic polymorphisms would call for modifying these strategies and how bloodwork can be used to monitor the results.
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