Presenter: Rudolph Tanzi, PhD
Format: MP4 Video file of Slides and Audio

Alzheimer’s disease is the most common form of dementia affecting the elderly and is characterized by global cognitive decline in learning, memory, reasoning and judgment. AD is strongly influenced by both genetic factors and lifestyle. While certain rare gene mutations, e.g. in the APP, PSEN1 and PSEN2 genes guarantee onset of AD before 60 years old, most cases of AD (>97%) involve genetic susceptibility factors and lifestyle, e.g. diet, exercise, intellectual stimulation and social engagement, stress levels and trauma, as well as sleep patterns. In addition, the effects of Alzheimer’s disease on the brain, mind, and consciousness will be considered. In particular, the question of how the concept of “self “can be further refined in view of the effects of Alzheimer’s on the brain and mind will be discussed. Further elucidation of the relationship between brain function, mind, consciousness, and the cosmos will also be presented based on the concepts of neuroplasticity.

1. The etiology and pathogenesis of Alzheimer’s disease (AD)
2. The genetic basis of AD
3. Therapeutics for AD: Now and in the Future
4. Effects of AD on the brain, mind, and self
5. How to preserve brain health and help prevent AD with lifestyle interventions